Wednesday, October 28, 2009

Preventing diabetes: lose weight first

For people at risk for type 2 diabetes, weight loss is central to preventing the onset of the disease.

  This was said Dr. David Nathan, in 20th World Congress on Diabetes, which was attended by more than 10 000 specialists in Montreal from October 18 to 22.

"Every pound lost is equivalent to a risk reduction of 16%," he says. Conversely, having a body mass index (BMI) greater than 35 increased from 91% risk of developing diabetes over a period of 14 years.

  American scientist attached to the Massachusetts General Hospital, Dr. Nathan is the author of a major study - Diabetes Prevention Program (DPP) 1 - published in 2002 and conducted among 3 200 people pre-diabetic. The results show that it is possible to prevent and combat diabetes simply by changing his lifestyle. He has since signed more than 100 studies on diabetes.

Until then, we believed only virtues of the pharmaceutical approach to living with the disease advances there. "But we know now that even those newly diagnosed with diabetes, a 10% weight helps control blood sugar and pressure by reducing the use of drugs," said David M. Nathan 2.

No need to go to the gym

Besides heredity, or certain genetic predispositions, the main risk factors for diabetes are related to modifiable behaviors: diet high in saturated fat, abdominal obesity, hypertension and sedentary lifestyle.

That is what has retarded the DPP: the program was a change in behavior of participants in setting realistic goals and tailored to participants' daily.

"No need to enroll in a gym or a cooking class: it was enough, for example, walking at a brisk pace at 150 minutes per week and change his diet to lose 5% to 10 % of body weight - notably by reducing by 25% the amount of saturated fat, "says Dr. Nathan.

The DPP, which continues today, is not the only one to have given similar results. Similar studies conducted in Japan, Finland and India, have also shown that it is possible to prevent diabetes in people at risk by changing some habits.
Preventing with or without medication?

In a forum where he discussed with Dr. Jean-Louis Chiasson, University of Montreal, Dr. Nathan said that weight loss combined with physical activity also reduces the risk of metabolic syndrome 41%. And even reverse glucose intolerance.

"Besides edit and lifestyle can reduce the risk of certain risk factors for cardiovascular diseases including hypertension, bad cholesterol and chronic inflammation," he listed.

  But is it realistic to believe that people at high risk of diabetes adopt better habits of life and they keep the long term? This is the real issue, according to Dr. Chiasson.

"We can prevent the disease by eating better and moving more, but it is true that if we persevere, says he. Now we know that after 3 years, only 10% of participants continue their good habits. "

According to Dr. Chiasson, this is a problem that requires medication. And he argues that another drug - acarbose - can do better than metformin. "Acarbose was more effective in preventing diabetes and reducing the risk of cardiovascular disease in all age groups," he said.

But Dr. David Nathan persists. "In Finland, a study has shown that the effect of healthy lifestyle reduced by 58% the risk of developing diabetes after 4 years. And among those who continued to move and eat better after 7 years the risk was further reduced by 43%, excluding the effect on their quality of life in general - that are not drugs, "he said .

In 2010, Canada will have more than 3 million with type 2 diabetes. About 60% suffer from hypertension, and a similar percentage has a high cholesterol, making them at risk for cardiovascular disease.

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