Influenza A: adjuvants like squalene are they dangerous?

The case of squalene suitable as an adjuvant in the vaccine against influenza A
Squalene is used in the adjuvant vaccine to influenza A containing adjuvant and the human papillomavirus (HPV).
Squalene is a natural oil that is found in certain plants, animals and humans, but also in certain foods, cosmetics and food supplements.
Squalene is also used in some pharmaceuticals and some vaccines (Influenza A, HPV ..).


The AFSSAPS

According Afssaps, the French Agency for the Safety of Health Products, adjuvants based on squalene used in vaccines for influenza A did not appear, according to experiments on animals and studies in the man risks apart from an increase in local reactions (pain, redness ..) at the injection site.

WHO

According to WHO, more than 22 million doses of influenza vaccine containing squalene were administered, mainly in older age groups.

The safety of squalene in vaccines
The Global Advisory Committee on Vaccine Safety (GACVS) studied repeatedly question the safety of adjuvants, in particular squalene adjuvants containing it.
22 million doses of flu vaccine from Chiron (the FLUAD) were administered without safety concerns since 1977, apart from mild local reactions.
In infants and newborns, clinical studies on vaccines containing squalene performed revealed no problems severe enough to raise concerns.